My Cart 
Biomedical Spectroscopy Applications
Biomedical spectroscopy plays an important role in clinical diagnostics, life science research, and medical device development. These applications often require high-performance spectrometers with excellent sensitivity, low stray light, fast acquisition speeds, and wavelength flexibility. Avantes has extensive experience providing fiber-optic spectroscopy solutions for demanding biomedical and clinical applications, including both non-invasive and invasive measurements.
Spectroscopy for Clinical Diagnostics and Life Sciences
Avantes spectrometers can be configured and validated for a wide range of biomedical spectroscopy applications, including co-oximetry, pulse oximetry, fluorescence spectroscopy, diffuse reflectance spectroscopy, tissue perfusion monitoring, endoscopy, and cancer detection.
For co-oximetry, the VARIUS™ spectrometer can be configured and validated for integration into clinical analyzers to measure blood parameters such as hemoglobin, carboxyhemoglobin, bilirubin, and other blood-related optical signals. Spectroscopy enables these systems to distinguish and quantify different blood components based on their wavelength-dependent absorption characteristics.
Avantes spectrometers can also be configured for pulse oximetry and tissue oxygenation measurements, where optical spectroscopy is used to monitor blood oxygen saturation and tissue oxygen consumption. The flexibility of the VARIUS™ platform makes it suitable for development and validation across a variety of demanding biomedical and clinical measurement requirements.
High-Performance Spectrometers for Biomedical Research
For applications requiring high-speed measurements, the AvaSpec-HS2048XL-EVO supports rapid fluorescence spectroscopy during needle biopsies, as well as diffuse reflectance measurements for endoscopy and deep-tissue mass detection. These techniques can provide valuable optical information about biological tissue and support the development of advanced diagnostic and medical imaging systems.
Avantes OEM spectrometers provide additional flexibility for biomedical instrumentation manufacturers. Spectrometers can be configured to meet application-specific requirements for wavelength range, resolution, sensitivity, speed, stray light, and physical integration.
Quality and Reliability for Biomedical Applications
Biomedical and clinical instrumentation requires reliable, stable, and traceable components. Avantes’ commitment to quality includes ISO certification, a three-year warranty, 8-hour thermal testing of instruments, and 100% traceability of subcomponent parts. These quality measures help ensure the stability and robustness required for integration into demanding biomedical and medical devices.
With a broad selection of spectrometers, light sources, fiber-optic components, and accessories, Avantes provides configurable spectroscopy solutions for biomedical research, clinical diagnostics, medical device development, tissue analysis, life science research, and non-invasive medical measurements.
Biomedical Spectroscopy Applications
Avantes instrumentation has been implemented or evaluated for applications across numerous medical specialties, including:
- Angiology and pharmacology: Monitoring tissue oxygen saturation following the application of vasoactive pharmaceuticals, including studies of oxygenation changes associated with Raynaud syndrome and microcirculation disorders.
- Dermatology and tissue transplantation: Detecting blood perfusion in grafted tissues and using non-invasive diffuse reflectance measurements to identify melanoma and other dermal abnormalities.
- Endocrinology: Supporting the detection of microangiopathy, endothelial dysfunction, and ulceration through optical tissue measurements.
- Cardiac surgery: Integration of Avantes instruments into clinical devices to monitor cardiac oxygen consumption during and following bypass operations.
- Neurosurgery and oncology: Measuring brain tumor oxygen consumption before and after radiation treatment or surgery, as well as evaluating the efficacy of radiation therapy through measurements associated with breast mass reduction.
- Pediatric medicine: Integration of low-stray-light Avantes spectrometers into clinical devices for monitoring blood parameters in critically ill newborns.
- Plastic surgery and transplantation medicine: Monitoring the vascularization and perfusion of transplanted tissues and organs.
- Otorhinolaryngology: Using endoscopic spectroscopy to characterize throat tissues for abnormalities and cancer detection.
- Trauma surgery: Non-invasive optical characterization of burned or frozen tissue to help assess tissue condition.
- Cancer detection and smart biopsy: Avantes miniature spectrometers have been used in research involving spectroscopic cancer detection and smart biopsy needles, including applications for real-time tissue characterization.
